Category: Medical Research

Symptoms that you may be infected with Coronavirus / COVID-19

The symptoms shown by those infected with Coronavirus can vary widely. When searching the Internet, for symptom lists, you will find that often (but not always the Symptoms of a COVID-19 infection are similar to those found with respiratory illnesses including the flu and common cold. They include:

  • Cough – usually a Dry Cough
  • Sneezing
  • Fever
  • Sore throat
  • Difficulty breathing
  • Pneumonia in severe cases

Video is courtesy of the Science Insider YouTube channel.

Two unique symptoms which have recently been discovered, is the loss of Taste and Smell. One person described it to be like eating some Chocolate Ice cream and not being about to discern the Chocolate taste. The loss of one’s sense of smell can also point to a Coronavirus infection.

Stomach issues have also been mentioned by people who have suffered thru thru COVID-19 infection. One person mentioned pain in her stomach and wanting badly to burp but unable to do so.

Diarrhea has also been mentioned. Along with that is the idea of Fecal transmission of COVID-19. It is recommended to close the lid on a toilet before flushing. That would limit the spread of particles into the air in the washroom.

I might suggest that if at all possible, to limit the use of Public Washrooms. It is not just the idea of Fecal Transfer but an infected person would touch the Toilet’s Flush handle potentially leaving COVID-19 particles on the handle. If using a Public Washroom, please make sure to wash your hands using plenty of soap and hot water before leaving the Washroom. If possible dry your hands using paper towels. Why? It has been said the the hot air hand dryers may spread the  COVID-19 virus particles into the air, which you then breathe.

For more info about Coronavirus Symptoms you can visit the Mayo Clinic’s website by clicking on this link.

Click on this link to visit a website setup by the Government of Canada to provide info about Coronavirus / COVID-19.

Facts about Vitamin D and Immunity. Vitamin D can protect against Colds and Flu

There was also an informative article published by The Harvard Gazette. Click on the link to view that article:
“Study confirms vitamin D protects against colds and flu”

This info about Vitamin D may also help patients suffering for Coronavirus. See a prior post on this site for more info about Vitamin D and Coronavirus.

Can early and high intravenous dose of vitamin C prevent and treat Coronavirus 2019 (COVID-19)?

Vitamin C is not a patented drug and so is low cost. The use of Vitamin C as a treatment protocol for Coronavirus infections is rarely mentioned in the main news media. When one gets sick, Vitamin C  in your body is depleted.

There were initial reports out of China that Coronavirus patients were being given intravenous Vitamin C. Vitamin C is also know to help patients who get Sepsis, which can also be the result of acquiring Coronavirus.

Some New York Hospitals have also treated Coronavirus patients with intravenous Vitamin C.

A new report has been published by Medicine in Drug Discovery, a peer reviewed journal by Elsevier, which details treating Coronavirus Patients using intravenous Vitamin C.

Click on the report title link below to visit the Elsevier’s Medicine in Drug Discovery site to read the report:

Can early and high intravenous dose of vitamin C prevent and treat Coronavirus disease 2019 (COVID-19)?

The report is as follows courtesy of Elsevier and Medicine in Drug Discovery:

Author links open overlay panel Richard Z.Cheng

Under a Creative Commons license
open access

The COVID-19 (SARS-2-Cov) pandemic, first reported in Wuhan, China, is now spreading to many continents and countries, causing a severe public health burden. Currently, there is no vaccine or specific antiviral drug for this deadly disease. A quick, deployable and accessible, effective and safe treatment is urgently needed to save lives and curtail the spreading. Acute respiratory distress syndrome (ARDS) is a key factor of fatality. Significantly increased oxidative stress due to rapid release of free radicals and cytokines is the hallmark of ARDS which leads to cellular injury, organ failure and death. Early use of large dose antioxidants, such as vitamin C (VC) may become an effective treatment for these patients. Clinical studies also show that high-dose oral VC provides certain protection against viral infection. Neither intravenous nor oral administration of high-dose VC is associated with significant side effects. Therefore, this regimen should be included in the treatment of COVID-19 and used as a preventative measure for susceptible populations such as healthcare workers with higher exposure risks.

Coronaviruses and influenza are among the pandemic viruses that can cause lethal lung injuries and death from ARDS [[1][2][3]]. Viral infections could evoke “cytokine storm” that leads to lung capillary endothelial cell activation, neutrophil infiltration and increased oxidative stress (reactive oxygen and nitrogen species). ARDS, characteristic of severe hypoxemia, is usually accompanied by uncontrolled inflammation, oxidative injury and damage to the alveolar-capillary barrier [4]. Increased oxidative stress is a major insult in pulmonary injury including acute lung injury (ALI) and ARDS, two clinical manifestations of acute respiratory failure with substantially high morbidity and mortality [5,6].

In a report of 29 patients with COVID-19 pneumonia, 27 (93%) showed increased hsCRP, a marker of inflammation and oxidative stress [7]. Transcription factor, nuclear factor erythroid 2 (nfe2)-related factor 2 (nrf2), is a major regulator of antioxidant response element (ARE)-driven cytoprotective protein expression. Activation of Nrf2 signaling plays an essential role in preventing cells and tissues from injury induced by oxidative stress. VC, an important component of the cellular antioxidant system [8], is beneficial to critical care management [9]. Cytokine storm is observed in both viral and bacterial infections [3] and results in increased oxidative stress via a common and non-specific pathway. Since the prevention and management of oxidative stress could be realized by large dose of antioxidants, this approach may be applicable to COVID-19 with intravenous high-dose VC based on the outcome of three previous clinical studies involving a total of 146 patients with sepsis [10].

Hemila and colleagues reported that various high-dose intravenous VC infusions (e.g., 200 mg/kg body weight/day, divided into 4 doses) shortened the intensive care unit (ICU) stay by 97.8% [11], accompanied by a significant reduction in the mortality rate [12]. Such an experience was reproduced among patients ill with severe influenza [13,14]. Indeed, dietary antioxidants (VC and sulforaphane) were shown to decrease oxidative stress induced acute inflammatory lung injury in patients receiving mechanical ventilation [15]. In addition, oral VC (e.g., 6 g daily) was able to reduce viral infection risk [16] or to improve symptoms [17].

High-dose intravenous VC has also been successfully used in the treatment of 50 moderate to severe COVID-19 patients in China. The doses used varied between 2 g and 10 g per day, given over a period of 8–10 h. Additional VC bolus may be required among patients in critical conditions. The oxygenation index was improving in real time and all the patients eventually cured and were discharged [18]. In fact, high-dose VC has been clinically used for several decades and a recent NIH expert panel document states clearly that this regimen (1.5 g/kg body weight) is safe and without major adverse events [19].

Because the development of efficacious vaccines and antiviral drugs takes time, VC and other antioxidants are among currently available agents to mitigate COVID-19 associated ARDS. Given the fact that high-dose VC is safe, healthcare professionals should take a close look at this opportunity. Obviously, well-designed clinical studies are absolutely needed to develop standard protocols for bedside use.

References

Vitamin D could be an adjunctive treatment protocol to help patients with Coronavirus.

Severe Coronavirus infections could result in the patient getting an acute respiratory Tract Infection requiring the use of a Ventilator to sustain life. Vitamin D could be an adjunctive treatment protocol to help patients with Coronavirus.

Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS)

https://scholar.harvard.edu/kennethbchristopher/publications/vitamin-d-deficiency-contributes-directly-acute-respiratory

Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data

https://www.bmj.com/content/356/bmj.i6583

Low Vitamin D Status Occurs in 90% of Patients with ARDS and Is Associated with Longer Duration of Mechanical Ventilation

https://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2016.193.1_MeetingAbstracts.A1846

Please discuss the above with your Medical Doctor to see if the information may be of help. Self Medicating without the advice of your Medical Doctor(s) is not recommended.

The Truth About Cell Phone Radiation and 5G by Theodora Scarato

The Truth About Cell Phone Radiation and 5G by Theodora Scarato.

Video is courtesy of the The Real Truth About Health YouTube channel

New York, NY, July 22, 2019. The Advisors to the International EMF Scientist Appeal, representing 248 scientists from 42 nations, have resubmitted The Appeal to the United Nations Environment Programme (UNEP) Executive Director, Inger Andersen, requesting the UNEP reassess the potential biological impacts of next generation 4G and 5G telecommunication technologies to plants, animals and humans.

There is particular urgency at this time as new antennas will be densely located throughout residential neighborhoods using much higher frequencies, with greater biologically disruptive pulsations, more dangerous signaling characteristics, plus transmitting equipment on, and inside, homes and buildings. The Advisors to The Appeal recommend UNEP seriously weigh heavily the findings of the independent, non-industry associated EMF science

Click on this link to view the PDF file of the complete Press Release and it links to the recent letter to the UN Environment Programme (UNEP).

Click on this link to read the new article posted by Dr. Devra Davis titled: “Pending Government Immunity for Telecoms Uninsurable 5G Network?“.

Click on this link to view: The National Toxicology Program (NTP) concluded in two final reports released November 1, 2018, that there is clear evidence that male rats exposed to high levels of radio frequency radiation (RFR), like that used in 2G and 3G cell phones, developed cancerous heart tumors. There was also some evidence of tumors in the brain and adrenal gland of exposed male rats.

 

Posted by Vincent Banial

The truth about mobile phone and wireless radiation by Dr. Devra Davis

What are the health effects of mobile phones and wireless radiation?

The truth about mobile phone and wireless radiation by Dr. Devra Davis.

In this Dean’s Lecture, epidemiologist and electromagnetic radiation expert, Dr. Devra Davis, will outline the evolution of the mobile phone and smartphone, and provide a background to the current 19 year old radiation safety standards (SAR), policy developments and international legislation. New global studies on the health consequences of mobile/wireless radiation will be presented, including children’s exposure and risks.

Video is courtesy of the The University of Melbourne YouTube channel

 

There is also a great Time Magazine article which discussed Dr. Devra Davis’s research into Wireless radiation. Click on this link to visit the Time.com website to read their posted article titled: “Health: A Cancer Muckraker Takes on Cell Phones“.

 

Posted by Vincent Banial

Using Brewer’s Yeast to produce Marijuana’s main ingredients : mind-altering THC and non-psychoactive CBD

You no longer need to grow a Marijuana plant to extract THC and CBD. You can get both by using Brewer’s Yeast and Sugar. You also get purer products. For example you can make CBD without the worry of it also containing THC.

This is revolutionary. It could eliminate huge Marijuana plant grow operations. It could also produce Cannabinoids which cannot be obtained from Marijuana plants. The consistency and purity of the produced product can be regulated to be uniform from batch to batch. This new process offers great potential in finding, via Medical Research Studies, new medical benefits of THC, CBD and other Cannabinoids.

Cristina Sánchez has been studying Cannabis for fifteen years  at Complutense University in Madrid Spain.  She has discovered that THC from Cannabis can kill Cancer cells.

Dr Christina Sanchez explains how cannabis kills cancer cell from Life With Cannabis on Vimeo.

Being able to produce Medical Cannabis products like THC in a pure form using Brewer’s Yeast opens up a lot of potential in the Medical field as you can maintain purity and quality  in each batch produced. For example, there have been documented  cases of patients who have seizures and are helped by CBD. You also eliminate the potential use of Pesticides in Plant Grow Operations.

Click on this link to visit the ScienceDaily website to read the newly published research from the University of California – Berkeley: “Yeast produce low-cost, high-quality cannabinoids.” ScienceDaily. ScienceDaily, 27 February 2019. <www.sciencedaily.com/releases/2019/02/190227131838.htm>.

Click on this link to visit the website of the journal Nature and read the abstract of the February 27 2019 published research article titled: “Complete biosynthesis of cannabinoids and their unnatural analogues in yeast“.

Click on this link to visit the ScienceDaily website to read the research report titled: “Benefits of medical marijuana for treatment of epilepsy examined

Click on this link to visit the Bloomberg website to read their page about Demetrix Inc.

The information provided about cannabis is for informational purposes only. Please consult your physician before making any medical decisions.

Posted by Vincent Banial

New Medical Study sheds light on P. gingivalis colonization in a Human Brain as being the cause of developing Alzheimer’s Disease. The study also found that 100% of patients with Cardiovascular Disease had P. gingivalis arterial colonization.

Having Bad Breath could be a Major Risk Factor in developing Alzheimer’s Disease and Cardiovascular Disease.

A new Medical Study just released sheds light on P. gingivalis colonization in a human Brain as being the cause of developing Alzheimer’s Disease. The study also found that 100% of patients with Cardiovascular Disease had P. gingivalis arterial colonization.

The medical study is published by American Association for the Advancement of ScienceScience Advances. Click on this link to visit the Science Advances site to read the study titled “Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors“.

The following are brief excerpts (you can read the full Study at the link noted above) from this new Research Study:

“The bacterium called gingipains (P. gingivalis) were identified in the brain of Alzheimer’s patients.”

Video is courtesy of OSH News Network YouTube Channel

Oral P. gingivalis infection in mice resulted in brain colonization and increased production of Aβ1–42, a component of amyloid plaques. Further, gingipains were neurotoxic in vivo and in vitro, exerting detrimental effects on tau, a protein needed for normal neuronal function.”

“Alzheimer’s disease (AD) patients exhibit neuroinflammation consistent with infection, including microglial activation, inflammasome activation, complement activation, and altered cytokine profiles (1, 2). Infectious agents have been found in the brain and postulated to be involved with AD, but robust evidence of causation has not been established (3).”

“In Apoe−/− mice, oral infection with P. gingivalis, but not with two other oral bacteria, results in brain infection and activation of the complement pathway (14). In transgenic mice overexpressing mutated human amyloid precursor protein (hAPP-J20), oral infection with P. gingivalis impairs cognitive function, increases the deposition of AD-like plaques, and results in alveolar bone loss compared to control hAPP-J20 mice (15). P. gingivalis lipopolysaccharide has been detected in human AD brains (16), promoting the hypothesis that P. gingivalis infection of the brain plays a role in AD pathogenesis (17).”

“P. gingivalis is mainly found during gingival and periodontal infections; however, it can also be found at low levels in 25% of healthy individuals with no oral disease (18). Transient bacteremia of P. gingivalis can occur during common activities such as brushing, flossing, and chewing, as well as during dental procedures (19), resulting in documented translocation to a variety of tissues including coronary arteries (20), placenta (21), and liver (22).”

“A recent study found that 100% of patients with cardiovascular disease had P. gingivalis arterial colonization.” (23).

Video is courtesy of John Douillard YouTube Channel

Click on this link to visit the New Scientist website to reqd their article titled “We may finally know what causes Alzheimer’s – and how to stop it“.

Posted by: Vincent Banial

Pirate Queen of Academic Research Papers

Really insightful article about about who owns academic research online.

Over half of all research, according to one study, is now published by the big five of academic publishing. To view research papers one has to go thru a paywall and pay for access to each research paper.

Most academic research is funded by Governmental Agencies. So the Taxed payers pay for the research to be done. Ask yourself this question: Since Tax Payer money funded the Academic Research, then should all resulting research papers be available to read for free?”

Video is courtesy of the Life Extension Advocacy Foundation YouTube Channel

Unfortunately at present if you want to view the results and read the published research papers one has to pay the private publishers via website Paywalls to access the research papers.

A new alternative has appeared, that being Open Access: “free availability on the public internet,” Click on this line to visit PLOS ONE – an Open Access site

This really good article is about Alexandra Elbakyan, a gifted programmer, who setup Sci-Hub – a site where one can download research papers for free.

The major publishers of Academic Research papers make a fortune and see Open Access and Alexandra’s Sci-Hub as cutting into their profits and ability to Hoard ever More Money by raising prices. So they have sued Alexandra Elbakyan. The lawsuits have impacted Internet Service providers and some believe hinder a free and open Internet.

Click on this line to the visit The Verge website to read their article titled:

“Science’s Pirate Queen”.

 

The results from 2 Medical Studies indicate that Meditation and Exercise can dramatically reduce the incidence, duration and severity of colds and the flu

The results from 2 Medical Studies indicate that Meditation and Exercise can dramatically reduce the incidence, duration and severity of colds and the flu.

Dr. Bruce Barrett, at the UW-Madison headed up the research in the first study.  He commented on the results from the study by saying “this could be more powerful than flu shots,“.

The 150 study participants were split into 3 groups. One group received 8 weeks of Mediation training and were asked to continue to Meditate daily. The 2nd group was given Exercise classes and were asked to continue to exercise. The last group received no classes and did not Mediate for Exercise.

The results of that study were:

People in the meditation group had 33 percent fewer illnesses than the control group. Their illnesses were 43 percent shorter and were 60 percent less severe.

In the exercise group, the incidence, duration and severity of illnesses were reduced by 29 percent, 43 percent and 31 percent, respectively, according to the findings published in this month’s Annals of Family Medicine.

Both groups also missed less work.

The second study was published Published: June 22, 2018. It also took place in Madison Wisconsin. This study was undertaken by the following Medical Professionals:

Again the participants were split into 3 groups. One group received 8 weeks of Mindfulness based Stress Reduction (Meditation training). Another group received 8 weeks of training in moderate intensity sustained exercise. The last group (Control Group) did not meditate nor exercise daily.

The results of the study were that in the Meditation group, there were 112 ARI episodes and 1045 days of ARI illness, compared to 120 episodes and 1010 illness days in the group which exercised , compared with 134 episodes with 1210 days of ARI illness for the Control Group which did not Meditate or Exercise daily.

Practicing Mediation daily did significantly benefit the participants in the group which Mediated when compared to the participants in the group which neither Mediated daily nor Exercised.

I agree with the statement made by Dr Barrett that practicing Mediation daily “could be more powerful than flu shots,”. Big Pharma will likely not be overjoyed by the results of these two studies.

Click on this line to visit the Wisconsin State Journal website to read their article titled: ‘UW study: Exercise, meditation can help prevent cold and flu”.

Click on this line to visit the PLOS ONE website to read the published Medical study titled: “Meditation or exercise for preventing acute respiratory infection (MEPARI-2): A randomized controlled trial”.

 

 

THC inhibits growth and metastasis of Lung Cancer, per Research Study at the Beth Israel Deaconess Medical Center – Harvard University

Back in 2007, the American Association for Cancer Research published Information about research which was presented at their annual meeting by

The closing important paragraph from the Abstract published by the Cancer Research Journal is below:

Cumulatively, these studies indicate that THC has anti-tumorigenic and anti-metastatic effects against lung cancer. Novel therapies against EGFR overexpressing, aggressive and chemotherapy resistant lung cancers may include targeting the cannabinoids receptors.

Posted by: Vincent Banial

Harvard University discussion on the latest Scientific Findings about Medical Cannabis

Harvard University brought together researchers studying Marijuana’s health impacts with policymakers who are working to implement new laws in ways that will benefit and protect public health.

Video courtesy of the Harvard University YouTube channel

Click on this link to visit the National Cancer Institute website.

The following is from the National Cancer Institute webpage linked to above titled “Cannabis and Cannabinoids (PDQ®)–Patient Version
Questions and Answers About Cannabis”

Have any preclinical (laboratory or animal) studies been conducted using Cannabis or cannabinoids?

Preclinical studies of cannabinoids have investigated the following:

Antitumor activity

Studies in mice and rats have shown that cannabinoids may inhibit tumor growth by causing cell death, blocking cell growth, and blocking the development of blood vessels needed by tumors to grow. Laboratory and animal studies have shown that cannabinoids may be able to kill cancer cells while protecting normal cells.

A study in mice showed that cannabinoids may protect against inflammation of the colon and may have potential in reducing the risk of colon cancer, and possibly in its treatment.

A laboratory study of delta-9-THC in hepatocellular carcinoma (liver cancer) cells showed that it damaged or killed the cancer cells. The same study of delta-9-THC in mouse models of liver cancer showed that it had antitumor effects. Delta-9-THC has been shown to cause these effects by acting on molecules that may also be found in non-small cell lung cancer cells and breast cancer cells.

A laboratory study of cannabidiol (CBD) in estrogen receptor positive and estrogen receptor negative breast cancer cells showed that it caused cancer cell death while having little effect on normal breast cells. Studies in mouse models of metastatic breast cancer showed that cannabinoids may lessen the growth, number, and spread of tumors.

A review of 34 studies of cannabinoids in glioma tumor models found that all but one study showed that cannabinoids can kill cancer cells without harming normal cells.
A laboratory study of cannabidiol (CBD) in human glioma cells showed that when given along with chemotherapy, CBD may make chemotherapy more effective and increase cancer cell death without harming normal cells. Studies in mouse models of cancer showed that CBD together with delta-9-THC may make chemotherapy such as temozolomide more effective.

 

Posted by: Vincent Banial

The FDA approved Epidiolex (cannabidiol) [CBD] oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients two years of age and older.

Dr. Uma Dhanabalan, MD – Cannabis Therapeutics Specialist discusses Medical Cannabis


Dr. Uma V.A. Dhanabalan, MD, MPH, FAAFP, MRO is Board certified in Occupational Medicine, Medical Review Officer and Fellow of the American Academy of Family Physicians.


She is a Cannabis Therapeutics Specialist, doing Medical Marijuana authorizations. Her passion is in educating the public about Medical Cannabis and Endocannabinoid System.

Video is courtesy of the Georgia CARE YouTube channel

 

Dr. Uma V Dhanabalan MD MPH FAAFP speaks at the South Carolina Statehouse about Medical Cannabis as being a treatment Option for many illnesses


Dr. Uma V Dhanabalan MD MPH FAAFP speaks at the South Carolina Statehouse about Medical Cannabis as being a treatment Option for many illnesses.


She speaks from first hand experience seeing her patients health improve after treatment with Medical Cannabis

Note: This video’se volume level is really low and you may need headphones or external speakers

Video is courtesy of SC Compassionate Care Alliance YouTube channel

 

Matthew Walker discusses the latest discoveries why we sleep and how sleep impacts your life.


Professor Matthew Walker PhD, Director of UC Berkeley’s Sleep and Neuroimaging Lab discusses the latest discoveries about sleep and how it impacts our life, wellness, and lifespan.

Video is courtesy of the Talks at Google YouTube channel.

Click on this Link to visit Amazon.com to purchase Mathew Walker’s best selling book tilted: “Why We Sleep: Unlocking the Power of Sleep and Dreams.

PSA Testing for Prostate Cancer made No Significant Difference in Prostate Cancer Deaths after 10 years.

A new study has been published Mar 06 2018,  in the Peer-Reviewed Medical Journal called Journal of the American Medical Association (or JAMA). The Study found that PSA test screening did not achieve its aim of diagnosing fast-growing cancers in time to treat them and prevent Deaths.

Video is courtesy of the University of Bristol YouTube Channel

Title: Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer   Mortality: The CAP Randomized Clinical Trial
Author: Martin, Richard M.; Donovan, Jenny L.
Publication: JAMA
Publisher: American Medical Association
Date: Mar 6, 2018

There were men who were tested and the PSA Test found that they had a High PSA. Of those who agreed to further treatment during the study, some men were seriously harmed by treatment. There were 8 deaths in the screening group related to either the biopsy or prostate cancer treatment and 7 in the control group.

Click on this Link to the study published In JAMA on on Mar 06 2018 and titled “Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer MortalityThe CAP Randomized Clinical Trial.

Click on this link to visit the JAMA website and listen to an MP3 of the highlights of the Mar 06 2018 issue of the Journal of the American Medical Association.

Click on this Link to visit the Cancer Research UK website to read their post titled: “Why a one-off PSA test for prostate cancer is doing men more harm than good

Click on this link to visit The Telegraph newspaper website to read their article titled “Prostate screening saves no lives and may do more harm than good.

How effective is Chemotherapy as a treatment for Cancer?

Posted by Vincent Banial

Chemotherapy can be an effective treatment for Hodgkin’s disease (HD) – a type of lymphoma, which is a blood cancer. Chemotherapy can also be an effective form of treatment for Testicular Cancer.

What about other Cancers?

A study was published in the Dec 2004 issue of the Peer Reviewed Journal called Clinical Oncology, which addressed that question.

The following is taken from the abstract of that research Study :
“The overall contribution of curative and adjuvant cytotoxic chemotherapy to 5-year survival in adults was estimated to be 2.3% in Australia and 2.1% in the USA.”

The conclusion as found in the abstract was:
“it is clear that cytotoxic chemotherapy only makes a minor contribution to cancer survival. To justify the continued funding and availability of drugs used in cytotoxic chemotherapy, a rigorous evaluation of the cost-effectiveness and impact on quality of life is urgently required.”.

Found a link using a web search. The link is below ( you have to copy and paste the URL if you wish to visit their site – as you would from a web search):

http://healingpathwaysmedical.com/docs/chemotherapy-5-year-survival-stats.pdf

Basically that is supposed to be a PDF of the results from that study published on Dec 2004 in Clinical Oncology. It lists over twenty different Cancers and the percentage increases in 5 year survival rates for those patients who received Chemotherapy treatment for said Cancer.

Clinical Oncology had also published another research study in November 2004. You can view an abstract at nature.com by clicking on this line.

The following was the conclusion of the Nov 2004 published in Nov 2004:
“Adjuvant chemotherapy after potentially curative surgery can improve 5-year survival by 4% in patients with early-stage non-small-cell lung cancer (NSCLC, stages IB–IIIA).”.

So after surgery, Chemotherapy may increase the 5 year survival rate in about 4% of the patients. Yes, only 4%.

Using the above quoted studies and being overly generous, in my opinion it may seem that Chemotherapy does not increase the 5 year Survival Rate for about 85% of patients with many forms of Cancer. The exception is that yes it may be a form of effective treatment for Hodgkin’s Disease and for the treatment of Testicular Cancer.

With some Cancers the study chart (see the link to the PDF above) shows Chemotherapy to have zero effect on 5 years Survival Rate.

That leaves the question: Why is Chemotherapy being given to Cancer patients?

Disclaimer: The above is posted for information purposes only. I am not giving Medical Advice. If you have a medical issue please consult with your Licensed Medical Doctor, Specialist or other Medical Professional.

How Cannabis kills Cancer Cells by Dr, Christina Sanchez

How Cannabis kills Cancer Cells

by Dr, Christina Sanchez

Video is courtesy of the Lincoln Horsley YouTube channel

“Cannabis has been shown to kill cancer cells in the laboratory ” posted by the National Cancer Institue at cancer.gov

Something which has apparently been known in Cancer Research circles, has been formally announced to the public.

“Cannabis has been shown to kill cancer cells in the laboratory” posted by the National Cancer Institue at cancer.gov

Photo of a Marijuana / Cannabis plantPhoto courtesy of the United States Fish and Wildlife Service

The info  below is from the website of the National Cancer Institute (https://www.cancer.gov)

Cannabis and Cannabinoids (PDQ®)–Patient Version

Sections

Overview

  • Cannabis , also known as marijuana, is a plant grown in many parts of the world which produces a resin containing compounds called cannabinoids. Some cannabinoids are psychoactive (acting on the brain and changing mood or consciousness) (see Question 1).
  • The use of Cannabis for medicinal purposes dates back to ancient times (see Question 3).
  • By federal law, the possession of Cannabis is illegal in the United States outside of approved research settings. However, a growing number of states, territories, and the District of Columbia have enacted laws to legalize medical marijuana (see Question 1).
  • In the United States, Cannabis is a controlled substance requiring special licensing for its use (see Question 1 and Question 3).
  • Cannabinoids are active chemicals in Cannabis that cause drug -like effects throughout the body, including the central nervous system and the immune system (see Question 2).
  • The main active cannabinoid in Cannabis is delta-9-THC. Another active cannabinoid is cannabidiol (CBD), which may relieve pain, lower inflammation, and decrease anxiety without causing the “high” of delta-9-THC (see Question 2).
  • Cannabinoids can be taken by mouth, inhaled, or sprayed under the tongue (see Question 5).
  • Cannabis and cannabinoids have been studied in the laboratory and the clinic for relief of pain, nausea and vomiting, anxiety, and loss of appetite (see Question 6 and Question 7).
  • Cannabis and cannabinoids may have benefits in treating the symptoms of cancer or the side effects of cancer therapies. There is growing interest in treating children for symptoms such as nausea with Cannabis and cannabinoids, although studies are limited (see Question 7).
  • Two cannabinoids (dronabinol and nabilone) are drugs approved by the U.S. Food and Drug Administration (FDA) for the prevention or treatment of chemotherapy -related nausea and vomiting (see Question 7 and Question 10).
  • Cannabis has been shown to kill cancer cells in the laboratory (see Question 6).
  • At this time, there is not enough evidence to recommend that patients inhale or ingest Cannabis as a treatment for cancer-related symptoms or side effects of cancer therapy (see Question 7).
  • Cannabis is not approved by the FDA for use as a cancer treatment (see Question 9).

                           ******* end of post from cancer.gov *******

The following are additional links with info related to Cannabis and THC being able to kill Cancer Cells:

Antineoplastic Activity of Cannabinoids
http://www.ukcia.org/research/Antineo…

Cannabinoid Receptor Ligands Mediate Growth Inhibition & Cell Death In Mantle Cell Lymphoma
http://onlinelibrary.wiley.com/doi/10…

Δ9-Tetrahydrocannabinol Induces Apoptosis in Human Prostate PC-3 Cells via a Receptor-Independent Mechanism
http://onlinelibrary.wiley.com/doi/10…

Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma
http://jpet.aspetjournals.org/content…

Cannabinoid Receptors As Novel Targets for the Treatment of Melanoma
http://bbml.ucm.es/cannabis/archivos/…

DEA Eliminates 48-Year-Old Monopoly on Research-Grade Marijuana, Clearing Pathway for FDA Approval and Rescheduling

Cannabis plants
Photo of Cannabis plants courtesy of A7nubis and commons.wikimedia.org

Note from Vince: This is am extremely important change as the Cannabis grown by NIDA is an uncommon variety and apparently low in THC.  The FDA could approve a Medical Study of the use of high THC Cannabis in the treatment of Cancer, but NIDA always had the final word. If they approved a medical study (their usual common response was “No”) the study had to use the NIDA supplied Cannabis variety.

WASHINGTON, D.C. — Today, the Drug Enforcement Administration (DEA) announced their intention to grant licenses to additional marijuana growers for research, thereby ending the DEA-imposed 48-year monopoly on federally legal marijuana.  Since 1968, the University of Mississippi, under contract to the National Institute on Drug Abuse (NIDA), has maintained the only facility in the United States with federal permission to grow marijuana for research.

“It’s a complete and total end of the NIDA monopoly! There has been no production monopoly on any other Schedule I substance, like MDMA or LSD—only the cannabis plant. Licensing non-government cannabis producers, and thereby creating a path to FDA approval, will finally facilitate the removal of marijuana from Schedule I, and ultimately allow patients to receive insurance coverage for medical marijuana,” said Rick Doblin, Ph.D., Founder and Executive Director of the Multidisciplinary Association for Psychedelic Studies (MAPS).

MAPS has been working to eliminate this cannabis research blockade since 1999. NIDA’s marijuana is eligible for research, but cannot be sold as a prescription medicine, making it unacceptable to the Food and Drug Administration (FDA) for use in future Phase 3 studies.  Ending the monopoly finally allows for a pathway to FDA approval for marijuana, which would thereby trigger rescheduling.

In 2001, MAPS partnered with University of Massachusetts-Amherst Professor Lyle Craker, Ph.D., to apply for a DEA license and end the monopoly. In 2007, after years of bureaucratic delays and lengthy legal hearings, a DEA Administrative Law Judge (ALJ) recommended that it would be in the public’s interest to grant Craker the license. In 2009, after almost two more years of delays and less than a week before the inauguration of President Obama, former DEA Administrator Michelle Leonhart rejected the ALJ recommendation. In 2011, Craker sued the DEA in the U.S. First Circuit Court of Appeals. In its 2013 decision, the Court uncritically accepted the DEA’s arguments that NIDA’s monopoly provided “an adequate supply produced under adequately competitive conditions.”

Since the 2013 decision, Craker’s argument that NIDA does not have an adequate supply has become significantly more apparent. NIDA has been unable to provide the strains requested for MAPS’ long-delayed Phase 2 clinical trial of smoked marijuana to treat symptoms of posttraumatic stress disorder (PTSD) in 76 U.S. veterans. As a result, the study is proceeding with lower potency marijuana than what MAPS researchers requested.

The DEA has previously claimed that U.S. international treaty obligations under the United Nations Single Convention on Narcotic Drugs (Single Convention) require a federal monopoly, but in April 2016, the State Department released a statement clarifying that the Single Convention does not in fact limit the number of U.S. marijuana producers.

Furthermore, the DEA’s 2009 rejection of the ALJ recommendation to license Craker relied heavily on a U.S. Department of Health and Human Services (HHS) protocol review process, which was eliminated in 2015.

MAPS’ upcoming Phase 2 clinical trial of marijuana for PTSD in veterans is in collaboration with investigators in Phoenix, Arizona, and at Johns Hopkins University, the University of Colorado, and the University of Pennsylvania. The study is funded by a $2.15 million grant to MAPS from the State of Colorado. The study has received full regulatory approval, and will be the first randomized controlled trial of whole plant marijuana as a treatment for PTSD.

Founded in 1986, MAPS is a non-profit research and educational organization working to evaluate the safety and efficacy of botanical marijuana as a potential prescription medicine for specific medical uses approved by the FDA.

MORE INFORMATION

Additional information can be found at maps.org/research/mmj/dea-license.

CONTACT:
Rick Doblin, Ph.D., MAPS Executive Director
rick@maps.org
617-276-7806

Natalie Ginsberg, MAPS Policy & Advocacy Manager
natalie@maps.org
917-520-5531

The above Press Release is courtesy of the Multidisciplinary Association for Psychedelic Studies (MAPS)  whose Mission Sates :

Mission

Founded in 1986, the Multidisciplinary Association for Psychedelic Studies (MAPS) is a 501(c)(3) non-profit research and educational organization that develops medical, legal, and cultural contexts for people to benefit from the careful uses of psychedelics and marijuana.

“Making Peace with Cannabis” by Zach Walsh, PhD, Assistant Professor in the UBC Department of Psychology

This TEDx Talk is titled “Making Peace with Cannabis“. It features Zach Walsh, PhD, who is an Assistant Professor in the UBC Department of Psychology and Co-Director for the Centre for the Advancement of Psychological Science and Law. He is also involved in a current study at UBC which is investigating treating PTSD using Medical Cannabis.

Video is courtesy of the TEDx Talks YouTube channel

How injecting THC and injecting Placebo into veins causes Paranoia, per the results of a poorly designed Oxford University Research Study

Oxford University had posted a News Post titled : “How cannabis causes paranoia”.

Clearly a poorly designed study or one designed to give a negative impression of Cannabis. The study was not about the normal use of Cannabis. It was a study where participants were injected with THC. In the Real World, no one does that.

First of all, they injected THC directly into the veins of participants. IN the Real World, Cannabis users “Do Not” consume Cannabis in that manner. They were only testing THC and not Cannabis. THC is a chemical found in Cannabis, but there are also other chemicals in the Cannabis Plant.

When you smoke or eat Cannabis, it takes time to consume the Joint or Muffin. It takes time for the THC (and other chemicals) to get into the bloodstream. The brain is slowly affected.

When you inject THC, (which “no one” does in the real world) your brain gets hit by the psychoactive chemical THC all at once. There are other Cannabinoids and other chemicals in Cannabis when smoked or eaten. Those other chemicals work with the THC. This test does not represent Cannabis. It represents Injecting THC.

Clearly this was a poorly designed Research Study.

I have never heard of people becoming Paranoid after smoking a joint. Getting the Giggles and laughing at stupid stuff – yes. Getting the Munchies and having a group order Pizza to be delivered – yes. Paranoia – nada.

A clear example is concerts. If you step off to the sidelines and look up you will see a haze of smoke rising from the audience. They are smoking Cannabis – it also has a specific fragrance. I remember Maple Leaf Gardens – same thing rising above the Audience. If large numbers of people were all experiencing Paranoia, they would be running for the exits (or at least a large number would). That has never happened. I have attended and photographed a heck of a lot of concerts and have never seen a mass exit of the audience after they smoked their Cannabis. They all seemed to dance and have fun and enjoyed the music.

Coachella, A recent outdoor concert in the California had an area where free Cannabis was available (to eat and smoke) to those with VIP tickets. Not one single person ran out of that area, because the Cannabis supposedly, as per the failed Oxford study, caused Paranoia.

The other rather interesting thing about that Oxford study is that 30% of the Placebo group “also experienced Paranoia” after being injected with Placebo.

Seems to me that participants lacked Trust in what was being injected into their arms. 50% of those injected with THC experienced Paranoid thoughts. 30% of the participants who were injected with a Placebo also experienced Paranoid thoughts. This is not a normal type of result for a Placebo Group. Interesting how the report of the study did not go into why the 30% of those injected with Placebo had experienced Paranoid thoughts…

I’ll give an example to clarify. Say you wanted to do a study of the effects of drinking two glasses of Red Cabernet Wine each day with your supper. Clearly injecting the equivalent amount of alcohol found in two glasses of Red Wine (12% Alcohol by volume) directly into study participants veins would have a totally different effect than drinking two glasses of wine with supper. No one would design such a sham of study and proclaim the results show the negative effect of drinking two glasses of Red Wine with your supper. Yet this is what was done in the above noted Oxford Study. They injected THC and their News Post was then titled “How Cannabis Causes Paranoia”. They only tested THC (the psychoactive cannabinoid found in Cannabis). They “did not test” using Cannabis. The THC was injected directly into the bloodstream of the participants. No Cannabis was ingested or smoked by the participant. Actually “no Cannabis was ever used” by the Oxford study participants.

That study was funded by the National Health Dept. Medical use of Cannabis is banned by the National Dept of Health. If one wants future Research Funding, does one rock the boat?

Click on this link to visit the University of Oxford website to read their News post titled “How Cannabis Causes Paranoia”.

Here is the URL incase the link has issues: http://www.ox.ac.uk/news/2014-07-16-how-cannabis-causes-paranoia

They could also have called the article
How injecting Placebo causes Paranoia.

Posted by Vincent Banial

Black Pepper Oil inhibited Cancer Cells proliferation by 3.5-86.8%.

Posted by Vincent Banial

The Medical Research Study was conducted by Bioactive Natural Products and Phytoceuticals, Department of Horticulture and National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA. The results were authored by Liu Y1, Yadev VR, Aggarwal BB, Nair MG.

Study “results suggest that black pepper and its constituents like hot pepper, exhibit anti-inflammatory, antioxidant and anticancer activities“.

The extracts of black pepper at 200 microg/mL and its compounds at 25 microg/mL inhibited LPO by 45-85%, COX enzymes by 31-80% and cancer cells proliferation by 3.5-86.8%.

Abstract

“Black pepper (Piper nigrum) and hot pepper (Capsicum spp.) are widely used in traditional medicines. Although hot Capsicum spp. extracts and its active principles, capsaicinoids, have been linked with anticancer and anti-inflammatory activities, whether black pepper and its active principle exhibit similar activities is not known. In this study, we have evaluated the antioxidant, anti-inflammatory and anticancer activities of extracts and compounds from black pepper by using proinflammatory transcription factor NF-kappaB, COX-1 and -2 enzymes, human tumor cell proliferation and lipid peroxidation (LPO). The capsaicinoids, the alkylamides, isolated from the hot pepper Scotch Bonnet were also used to compare the bioactivities of alkylamides and piperine from black pepper. All compounds derived from black pepper suppressed TNF-induced NF-kappaB activation, but alkyl amides, compound 4 from black pepper and 5 from hot pepper, were most effective. The human cancer cell proliferation inhibitory activities of piperine and alklyl amides in Capsicum and black pepper were dose dependant. The inhibitory concentrations 50% (IC50) of the alklylamides were in the range 13-200 microg/mL. The extracts of black pepper at 200 microg/mL and its compounds at 25 microg/mL inhibited LPO by 45-85%, COX enzymes by 31-80% and cancer cells proliferation by 3.5-86.8%. Overall, these results suggest that black pepper and its constituents like hot pepper, exhibit anti-inflammatory, antioxidant and anticancer activities.”.

Click on this line to visit the US National Library of Medicine National Institutes of Health PubMed site to read about this research titled “Inhibitory effects of black pepper (Piper nigrum) extracts and compounds on human tumor cell proliferation, cyclooxygenase enzymes, lipid peroxidation and nuclear transcription factor-kappa-B.

Metabolically starving Cancer Cells through diet and compressed oxygen, replacing chemotherapy, surgery, or radiation is a therapy developed by Dr. Dominic D’Agostino

Dr. Dominic D’Agostino is an Assistant Professor at the University of South Florida College Of Medicine, Molecular Pharmacology & Physiology where he develops and tests Metabolic Therapies, including alternative energy substrates and ketogenic agents for neurological disorders, Cancer and wound healing.

While studying the effects of gasses on the brains of Navy Seal divers, he developed an approach for metabolically starving Cancer Cells through diet and compressed oxygen, replacing chemotherapy, surgery, or radiation.

Video is courtesy of the TEDx Talks YouTube channel

Click on this link to visit the official US Government PubMed site to view research findings published by Dr. Dominic D’Agostino titled “Press-pulse: a novel therapeutic strategy for the metabolic management of cancer.”

Click on this link to visit the official site of Dr. Dominic D’Agostino.

Posted by Vincent Banial