Category: Cancer Treatment
PSA Testing for Prostate Cancer made No Significant Difference in Prostate Cancer Deaths after 10 years.
A new study has been published Mar 06 2018, in the Peer-Reviewed Medical Journal called Journal of the American Medical Association (or JAMA). The Study found that PSA test screening did not achieve its aim of diagnosing fast-growing cancers in time to treat them and prevent Deaths.
Video is courtesy of the University of Bristol YouTube Channel
Title: Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial
Author: Martin, Richard M.; Donovan, Jenny L.
Publication: JAMA
Publisher: American Medical Association
Date: Mar 6, 2018
There were men who were tested and the PSA Test found that they had a High PSA. Of those who agreed to further treatment during the study, some men were seriously harmed by treatment. There were 8 deaths in the screening group related to either the biopsy or prostate cancer treatment and 7 in the control group.
Click on this Link to the study published In JAMA on on Mar 06 2018 and titled “Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer MortalityThe CAP Randomized Clinical Trial“.
Click on this link to visit the JAMA website and listen to an MP3 of the highlights of the Mar 06 2018 issue of the Journal of the American Medical Association.
Click on this Link to visit the Cancer Research UK website to read their post titled: “Why a one-off PSA test for prostate cancer is doing men more harm than good“
Click on this link to visit The Telegraph newspaper website to read their article titled “Prostate screening saves no lives and may do more harm than good“.
“Cannabis has been shown to kill cancer cells in the laboratory ” posted by the National Cancer Institue at cancer.gov
Something which has apparently been known in Cancer Research circles, has been formally announced to the public.
“Cannabis has been shown to kill cancer cells in the laboratory” posted by the National Cancer Institue at cancer.gov
Photo courtesy of the United States Fish and Wildlife Service
The info below is from the website of the National Cancer Institute (https://www.cancer.gov)
Cannabis and Cannabinoids (PDQ®)–Patient Version
Sections
- Overview
- Questions and Answers About Cannabis
- Current Clinical Trials
- About This PDQ Summary
- General CAM Information
- Evaluation of CAM Therapies
- Questions to Ask Your Health Care Provider About CAM
- To Learn More About CAM
- View All Sections
Overview
- Cannabis , also known as marijuana, is a plant grown in many parts of the world which produces a resin containing compounds called cannabinoids. Some cannabinoids are psychoactive (acting on the brain and changing mood or consciousness) (see Question 1).
- The use of Cannabis for medicinal purposes dates back to ancient times (see Question 3).
- By federal law, the possession of Cannabis is illegal in the United States outside of approved research settings. However, a growing number of states, territories, and the District of Columbia have enacted laws to legalize medical marijuana (see Question 1).
- In the United States, Cannabis is a controlled substance requiring special licensing for its use (see Question 1 and Question 3).
- Cannabinoids are active chemicals in Cannabis that cause drug -like effects throughout the body, including the central nervous system and the immune system (see Question 2).
- The main active cannabinoid in Cannabis is delta-9-THC. Another active cannabinoid is cannabidiol (CBD), which may relieve pain, lower inflammation, and decrease anxiety without causing the “high” of delta-9-THC (see Question 2).
- Cannabinoids can be taken by mouth, inhaled, or sprayed under the tongue (see Question 5).
- Cannabis and cannabinoids have been studied in the laboratory and the clinic for relief of pain, nausea and vomiting, anxiety, and loss of appetite (see Question 6 and Question 7).
- Cannabis and cannabinoids may have benefits in treating the symptoms of cancer or the side effects of cancer therapies. There is growing interest in treating children for symptoms such as nausea with Cannabis and cannabinoids, although studies are limited (see Question 7).
- Two cannabinoids (dronabinol and nabilone) are drugs approved by the U.S. Food and Drug Administration (FDA) for the prevention or treatment of chemotherapy -related nausea and vomiting (see Question 7 and Question 10).
- Cannabis has been shown to kill cancer cells in the laboratory (see Question 6).
- At this time, there is not enough evidence to recommend that patients inhale or ingest Cannabis as a treatment for cancer-related symptoms or side effects of cancer therapy (see Question 7).
- Cannabis is not approved by the FDA for use as a cancer treatment (see Question 9).
******* end of post from cancer.gov *******
The following are additional links with info related to Cannabis and THC being able to kill Cancer Cells:
Antineoplastic Activity of Cannabinoids
http://www.ukcia.org/research/Antineo…
Cannabinoid Receptor Ligands Mediate Growth Inhibition & Cell Death In Mantle Cell Lymphoma
http://onlinelibrary.wiley.com/doi/10…
Δ9-Tetrahydrocannabinol Induces Apoptosis in Human Prostate PC-3 Cells via a Receptor-Independent Mechanism
http://onlinelibrary.wiley.com/doi/10…
Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma
http://jpet.aspetjournals.org/content…
Cannabinoid Receptors As Novel Targets for the Treatment of Melanoma
http://bbml.ucm.es/cannabis/archivos/…
Black Pepper Oil inhibited Cancer Cells proliferation by 3.5-86.8%.
Posted by Vincent Banial
The Medical Research Study was conducted by Bioactive Natural Products and Phytoceuticals, Department of Horticulture and National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA. The results were authored by Liu Y1, Yadev VR, Aggarwal BB, Nair MG.
Study “results suggest that black pepper and its constituents like hot pepper, exhibit anti-inflammatory, antioxidant and anticancer activities“.
“The extracts of black pepper at 200 microg/mL and its compounds at 25 microg/mL inhibited LPO by 45-85%, COX enzymes by 31-80% and cancer cells proliferation by 3.5-86.8%.“
“Abstract“
“Black pepper (Piper nigrum) and hot pepper (Capsicum spp.) are widely used in traditional medicines. Although hot Capsicum spp. extracts and its active principles, capsaicinoids, have been linked with anticancer and anti-inflammatory activities, whether black pepper and its active principle exhibit similar activities is not known. In this study, we have evaluated the antioxidant, anti-inflammatory and anticancer activities of extracts and compounds from black pepper by using proinflammatory transcription factor NF-kappaB, COX-1 and -2 enzymes, human tumor cell proliferation and lipid peroxidation (LPO). The capsaicinoids, the alkylamides, isolated from the hot pepper Scotch Bonnet were also used to compare the bioactivities of alkylamides and piperine from black pepper. All compounds derived from black pepper suppressed TNF-induced NF-kappaB activation, but alkyl amides, compound 4 from black pepper and 5 from hot pepper, were most effective. The human cancer cell proliferation inhibitory activities of piperine and alklyl amides in Capsicum and black pepper were dose dependant. The inhibitory concentrations 50% (IC50) of the alklylamides were in the range 13-200 microg/mL. The extracts of black pepper at 200 microg/mL and its compounds at 25 microg/mL inhibited LPO by 45-85%, COX enzymes by 31-80% and cancer cells proliferation by 3.5-86.8%. Overall, these results suggest that black pepper and its constituents like hot pepper, exhibit anti-inflammatory, antioxidant and anticancer activities.”.
Click on this line to visit the US National Library of Medicine National Institutes of Health PubMed site to read about this research titled “Inhibitory effects of black pepper (Piper nigrum) extracts and compounds on human tumor cell proliferation, cyclooxygenase enzymes, lipid peroxidation and nuclear transcription factor-kappa-B.
Metabolically starving Cancer Cells through diet and compressed oxygen, replacing chemotherapy, surgery, or radiation is a therapy developed by Dr. Dominic D’Agostino
Dr. Dominic D’Agostino is an Assistant Professor at the University of South Florida College Of Medicine, Molecular Pharmacology & Physiology where he develops and tests Metabolic Therapies, including alternative energy substrates and ketogenic agents for neurological disorders, Cancer and wound healing.
While studying the effects of gasses on the brains of Navy Seal divers, he developed an approach for metabolically starving Cancer Cells through diet and compressed oxygen, replacing chemotherapy, surgery, or radiation.
Video is courtesy of the TEDx Talks YouTube channel
Click on this link to visit the official site of Dr. Dominic D’Agostino.
Posted by Vincent Banial
Some believe that Cannabis / Marijuana is a Dangerous Drug. So how many people have died from overdosing on Cannabis?
The above link is from our new blog called Uniquely Cannabis. It’s the first post, with more to come.
Main focus of Uniquely Cannabis will be Medical Cannabis / Marijuana. The reason for creating it was that I had read that Cannabis could help those suffering from different Cancers including Leukemia.
I hope that the site will become an infobase about Medical Cannabis / Marijuana to help inform people. I had watched someone take their final breath, because they had Leukemia and nothing helped. Wish that I had known about Cannabis Oil. It might have helped. If it did, then life would have been vastly different.
Posted by Vincent Banial
Venclexta (Venetoclax) granted U.S. FDA approval for the treatment of patients with Chronic Lymphocytic Leukemia (CLL)
Venclexta (Venetoclax) is the first FDA-approved treatment that targets the B-cell lymphoma 2 (BCL-2) protein, which supports cancer cell growth and is over-expressed in many patients with Chronic Lymphocytic Leukemia (CLL).
The patient must have been previously treated with at least one other approved treatment protocol without success. Venclexta (Venetoclax) may be the Holy Mary drug to try when everything else failed.
Patients on the Venclexta (Venetoclax) regime must be monitored as their can be severe side effects. During Human Trails a number of patients developed upper respiratory issues such as Pneumonia.
Patients also have to maintain a level of hydration – 1.5 to 2 liters per day. If averse symptoms arise then hydration may be have to be added intravenously.
I think the biggest issue to patients getting access to this drug, is that the reported cost of the drug is approx $100,000 US per year.
Speak with your Oncologist or other Cancer Secialist, about Venclexta (Venetoclax), if you have diagnosed with Chronic Lymphocytic Leukemia (CLL).
Click on this Link to Download the FDA Fact Sheets PDF for Venclexta (Venetoclax).
Click on this Link which details the FDA Approval of Venclexta (Venetoclax).
Click on this Link to visit the official Venclexta (Venetoclax) website.
Click on this Link to visit the Drugs.com website to read their detailed pages about Venclexta (Venetoclax).
Click on this line to visit the The Genentech® Access to Care Foundation to see if you may qualify to get help the High Cost of being treated with Venclexta (Venetoclax). If you qualify, you may get Venclexta (Venetoclax) at no cost to you.
Posted by: Vincent Banial
http://www.uniquelytoronto.com
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