Category: Medical Breakthroughs
Intestinal microbiota metabolism producing Trimethylamine-N-Oxide (TMAO), may be a contributing factor in developing Cardiovascular Disease in Humans. Very important study just published in Nature Medicine.
Geschätzte Prävalenz von Herz-Kreislauferkrankungen in den USA estimated prevalence of cardiovascular disease in the U.S. (Photo credit: Wikipedia)
On April 07 2013 a new and extremely important study was published by the peer-reviewed journal Nature Medicine.
This new study clearly demonstrated that the metabolism by Intestinal Microbiota of Dietary L-Carnitine, a Trimethylamine abundant in red meat, produced Trimethylamine-N-Oxide (TMAO) and accelerated the development of Atherosclerosis in mice. This acceleration of Atherosclerosis did not occur, when the test group of mice were concurrently given antibiotics to suppress the population of Intestinal Microbiota.
Landmark study: Enterobacter cloacae B29, may causatively contribute to the development of Obesity & Insulin Resistance
Rough and smooth colony growth of Enterobacter cloacae bacteria on Tryptic Soy Broth agar. Obtained from the CDC Public Health Image Library. Image credit: CDC(PHIL #6552), 1983. (Photo credit: Wikipedia)
Gut microbiota may causatively contribute to the development of Obesity & Insulin Resistance. More work needs to be done in this important research area.
The new study is titled: An opportunistic pathogen isolated from the gut of an obese human causes obesity in germfree mice. Continue reading
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