Intestinal microbiota metabolism producing Trimethylamine-N-Oxide (TMAO), may be a contributing factor in developing Cardiovascular Disease in Humans. Very important study just published in Nature Medicine.

Geschätzte Prävalenz von Herz-Kreislauferkrank...

Geschätzte Prävalenz von Herz-Kreislauferkrankungen in den USA estimated prevalence of cardiovascular disease in the U.S. (Photo credit: Wikipedia)

On April 07 2013 a new and extremely important study was published by the peer-reviewed journal Nature Medicine.

This new study clearly demonstrated that the metabolism by Intestinal Microbiota of Dietary L-Carnitine, a Trimethylamine abundant in red meat, produced Trimethylamine-N-Oxide (TMAO) and accelerated the development of  Atherosclerosis in mice. This acceleration of Atherosclerosis did not occur, when the test group of mice were concurrently given antibiotics to suppress the population of Intestinal Microbiota.

The Abstract of the new study may be viewed and full copies of the published study ordered by clicking on the following link: Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

Last year another Landmark Study showed that certain Intestinal Bacteria were linked as a contributing factor to developing obesity and insulin resistance in humans. You can read that post by clicking on the following:  Landmark  study Enterobacter Cloacae B29 may causatively contribute to the development of obesity insulin resistance.


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Neither Nature Medicine, nor the Authors of this study are affiliated with this blog. They do not  endorse this blog.

I have tried to post a brief overview of the very important findings, of this new study. If a mistake was made, please let me know by email or comment and I will work to quickly make a  correction. Copies of the published study may be purchased from Nature Medicine, by clicking on the link included with the post above. I have tried to stay within the “Fair Use” provisions in my reporting of this study. I believe this study to be incredibly important. As such I had hoped that posting about it on this blog could help the study garner more attention.

Everything in this blog post is subject to change without notice.